The potential of institutions getting directly involved in crypto assets seems like it is getting closer as the potential infrastructure investments they look for are running low and/or have hige valuations. Custodial solutions are also here and help.
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Yep, not as easy to invest in the next coinbase as it was to invest in the original one. At some point they will turn to the coins themselves. Though, I would bet they stick predominantly to bitcoin, at least at first.