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RE: Intercellular Homeostasis

in #intercellular2 months ago (edited)

Vitamin C

https://lpi.oregonstate.edu/mic/vitamins/vitamin-C

Vitamin C and Immune Function

https://pmc.ncbi.nlm.nih.gov/articles/PMC5707683/

Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability

https://www.sciencedirect.com/science/article/pii/S1549963419302011

Vitamin C Promotes Epidermal Proliferation by Promoting DNA Demethylation of Proliferation-Related Genes in Human Epidermal Equivalents

https://www.sciencedirect.com/science/article/pii/S0022202X25004166

Link between aldehydes and premature aging revealed

https://www.news-medical.net/news/20240412/Link-between-aldehydes-and-premature-aging-revealed.aspx

Formaldehyde and De/Methylation in Age-Related Cognitive Impairment

https://pmc.ncbi.nlm.nih.gov/articles/PMC8231798/

Study reveals how formaldehyde alters gene expression through epigenetics

https://www.news-medical.net/news/20231102/Study-reveals-how-formaldehyde-alters-gene-expression-through-epigenetics.aspx

As an overview of the research, Dr. Esteller points out that "we have discovered that formaldehyde is an inhibitor of the MAT1A protein, which is the main producer of S-Adenosyl-L-Methionine (SAM) and this last molecule is the universal donor of the chemical group "methyl" that regulates epigenetic activity. Specifically, we found that exposure to formaldehyde induced a reduction in SAM content and caused the loss of methylation of histones, proteins that package our DNA and control the function of thousands of genes".

..

The ascorbate biosynthesis pathway in plants is known, but there is a way to go with understanding control and functions

https://pmc.ncbi.nlm.nih.gov/articles/PMC11066809/