I lived in a yurt in that part of Appalachia before and yup the mold is horrendous. Even with the yurt up on a deck I still had problems with the mold. I used to get really excited over fabric structures but anymore I do my best to avoid them when in the mountains. Currently I have been living in a big canvas tent (way south of the mountains) and have been super surprised that I have not had any mold issues.
Cheers and Hive on!